Having read The Colle Move by Move by Cyrus Lakdawala, Zuke 'Em-The Colle Zukertort Revolutionized & The Moment of Zuke by David I. Rudel, Killer Chess Opening Repertoire by Aaron Summerscale, Starting out: d-pawn attacks by Richard Palliser, Starting out: The Colle by Richard Palliser, played countless blitz and OTB games vs strong players 1800+, I can categorically say that the Colle is far from a one trick pony bud.
The Zuke is not designed to open up the centre, as I have said. Sometimes it happens when the Queen is on c7 and a rook on c1, but the idea is to fix the centre with Ne5 and then attack on the kingside. That is the basic plan of the "mainline". However, in meeting moves like Bf5/Bg4, Nc6, g6, b6, you will encounter quite mainline Slav, Chigorin and Queens Indian Defences.
I think the stereotype people have towards the Colle is based on the simple old main lines of the Colle-Koltanowski variation, which is pretty much a different beast despite starting the move e3 and the Ne5 plan.
In the write up to the excellent book Colle Move by Move by Cyrus Lakdawala, the promo blurb says,
White typically builds on solid foundations before unleashing an attack on the enemy king. This straightforward plan makes it particularly popular at club level, but the Colle is played successfully by Grandmasters too. Lakdawala covers both the main lines and the more aggressive Colle-Zukertort Attack.
I wouldn't suggest that the Colle Zuke or K are the greatest thing since sliced bread but they are perfectly sound, lead to some interesting attacking positions and are benefited practically by the stereotypes expressed on here. I recently played a 1900+ Fide-rated player and they explained that since I would be looking to open the centre with e4 they played c x d when the fact is, it is almost never played in the Zuke! Just goes to show!
