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1...c5 initiates the Sicilian Defense. It is absolutely a respectable opening, and I am surprised you've never seen it before. I'll just quote Wikipedia: The Sicilian is the most popular and best-scoring response to White's first move 1.e4. Opening 1.d4 is a statistically more successful opening for White because of the high success rate of the Sicilian ...


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Any answer to the question will be as dangerously biased as the database behind it, and moreover Stockfish will have other opening "reasons" than a human (I play 100% c5, and that even without knowing theory...), but here are some values from the database behind the Lichess analysis board, as number of games and white win-white loss: c5 - Sicilian ...


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