The "main line" of this "opening" is, I suppose, 1.a4 e5 2.Ra3 Bxa3 3.Nxa3. White is down by an exchange, say 1 1/2 pawns. He has developed his QN but to a bad square. This cannot possibly be good. However, there are some mitigating factors. White does have the two Bishops, and the dark square Bishop is unopposed. A polite way to describe the state of Whites development is that it "remains flexible". A strong, fast, player who has put themselves frequently into this situation knows what they have to do, even if some of it is just figuring out what to do with that Knight.
For Black the situation is not difficult in principle. They should find a way to exert pressure that is enough to make White concede to exchanges,
and then win the endgame, which means playing a long game. But this is risky against a fast player at a short time control. Black will need to spend much time strategizing an unfamiliar position, instead of engaging in a rapid flurry of traditional manoeuvres. For Jacobsen, this worked and there has been a brief flurry of interest in this "banned opening" even extending to imagining that it may have some objective merit. If the fad persists, people will prepare for it, and it will soon fade.
For chess.com, their anti-cheating measures involve assuming that unusually favorable statistics imply cheating, and it is hard to see what else they can do. It is however inevitable that even the best statistical methods can only be right most of the time, and must be wrong some of the time. Unusual statistics may simply imply unusual circumstances, and likelihood estimates usually ignore these. Chess.com relied on statistics
to discredit and ban Hans Niemann in the past, but eventually backed down.
They may back down on this.
To furnish the OP with an answer, playing a legitimate move is certainly not cheating (although deliberately playing a bad move might be seen as insulting and thereby applying psychological pressure). Although there is some statistical evidence that might suggest some other form of cheating, there is no direct evidence, and there is a plausible explanation without cheating. Magnus Carlsen supported this by playing the "banned opening" in a titled Tuesday
event with the predictable outcome that he placed lower that he normally would, but still finished high in the ranking.