For example, based on the database at lichess, after 1. e4, 46.3% of the master games continue with 1... c5 while only 23.4% of all games continue with 1... c5 (31.7% continue with 1... e5).
Another example: after 1. e4, the response 1... d5 (9.9%) is the fourth most popular response for all players, but for masters, 1... d5 (2.0%) is only the seventh most popular response.
What makes some openings more popular in master's games and less popular in lower-level games?